Abstract Background Oral methotrexate (MTX) is the first-line therapy for patients with rheumatoid arthritis (RA).However, approximately one quarter of patients discontinue MTX within 12 months.MTX failure, defined as MTX cessation or the addition of another anti-rheumatic drug, is usually due adverse event(s) and/or inefficacy.The aims of this stu

Background: The prevalence of overweight and obesity is increasing worldwide.Research has clarified that being overweight or obese can lead to disability in everyday life.Aim: The present study explores the association between the degrees of experienced disability in Danish female healthcare workers with a Body Mass Index (BMI) classified as being

The Pam/Highwire/RPM-1 (PHR) proteins are key regulators of neuronal development that function in axon extension and guidance, termination of axon outgrowth, and synapse formation.Outside of development, the PHR proteins also regulate axon regeneration and Wallerian degeneration.The PHR proteins function in part by acting as ubiquitin ligases that

Optimal scheduling of the conventional generating units for two different dynamic test systems are percolated in this paper.This paper compares and contrasts among three types of wind profile formulations, namely linear, quadratic, and cubic, which were used to calculate wind power from hourly wind speed to find the profile with the greatest penetr

Background and Aims: To date, more than 2,500 micro-RNAs (miRNAs) have been discovered and some of which are considered to play important roles in window of implantation (WOI).In this study, we aimed to evaluate the efficacy of a miRNA-based endometrial receptivity analysis (MIRA) in IVF patients.Method: Patients who were planning for frozen-thawed